Human antibody-based chemically induced dimerizers for cell therapeutic applications
December 4th, 2017 by Zachary B Hill
Human antibody-based chemically induced dimerizers for cell therapeutic applications
Human antibody-based chemically induced dimerizers for cell therapeutic applications, Published online: 04 December 2017; doi:10.1038/nchembio.2529
Selections with a phage-displayed antibody library against an existing protein–small-molecule complex enabled the generation of antibody-based chemically induced dimerizers (AbCIDs) with the properties necessary for use in regulating cell therapies.