Dual phenazine gene clusters enable diversification during biosynthesis
March 18th, 2019 by Yi-Ming Shi
Dual phenazine gene clusters enable diversification during biosynthesis
Dual phenazine gene clusters enable diversification during biosynthesis, Published online: 18 March 2019; doi:10.1038/s41589-019-0246-1
Enzymes from two discrete biosynthetic gene clusters in the entomopathogenic bacterium Xenorhabdus szentirmaii cooperate to produce a diverse array of phenazine natural products, including phenazine–peptide and phenazine–polyketide derivatives.Microbiology: A new language for small talk
April 13th, 2017 by Yi-Ming Shi
Nature Chemical Biology 13, 453 (2017). doi:10.1038/nchembio.2362
Authors: Yi-Ming Shi & Helge B Bode
A new signal–receptor pair involved in regulating biofilm formation and virulence was detected in Vibrio cholerae. Both the signal and the transcription factor belong to common classes of natural products and receptor proteins, suggesting widespread importance of related systems in nature.