Engineering yeast phospholipid metabolism for de novo oleoylethanolamide production
December 16th, 2019 by Yi Liu
Nature Chemical Biology, Published online: 16 December 2019; doi:10.1038/s41589-019-0431-2
A combinatorial engineering strategy encompassing pathway regulation, heterologous enzymes and subcellular trafficking enables repurposing of the phospholipid biosynthetic pathway in Saccharomyces cerevisiae for the production of oleoylethanolamide.