<i>O</i>-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response
August 20th, 2018 by Xingqian Zhang
O-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response
<i>O</i>-GlcNAc modification of eIF4GI acts as a translational switch in heat shock response, Published online: 20 August 2018; doi:10.1038/s41589-018-0120-6
O-GlcNAcylation of translation initiation factor component eIF4GI blocks interactions to poly(A)-binding protein Pab1 to induce disassembly of stress granules, releasing Hsp70-induced mRNAs and leading to translation of protective proteins