A lanthipeptide library used to identify a protein–protein interaction inhibitor
March 5th, 2018 by Xiao Yang
A lanthipeptide library used to identify a protein–protein interaction inhibitor
A lanthipeptide library used to identify a protein–protein interaction inhibitor, Published online: 05 March 2018; doi:10.1038/s41589-018-0008-5
The substrate-tolerant lanthipeptide synthetase ProcM enables the construction of a plasmid-encoded library of bicyclic lanthipeptides, from which an inhibitor of the p6–UEV protein–protein interaction is identified by a reverse two-hybrid screen.