A dual function PUS enzyme

January 23rd, 2020 by Wen Zhang

Nature Chemical Biology, Published online: 23 January 2020; doi:10.1038/s41589-019-0450-z

The traditional function of pseudouridine synthases is to convert uridine residues in RNA to pseudouridines. A study reveals a new function for the human PUS10 protein, which enhances micro-RNA maturation in addition to tRNA modification.