Protein engineering: Beating the odds
December 7th, 2015 by Uwe T Bornscheuer
Nature Chemical Biology 12, 54 (2016). doi:10.1038/nchembio.1989
Author: Uwe T Bornscheuer
Recently developed advanced microfluidics-based systems have outperformed known screening tools with respect to throughput, flexibility, sensitivity and tricks for hit recovery. This has enabled the discovery of novel and improved proteins from random mutagenesis libraries or metagenome-based sources.