Insulating proteins drop by drop

August 2nd, 2021 by Ulrich Krauss

Nature Chemical Biology, Published online: 02 August 2021; doi:10.1038/s41589-021-00846-y

Liquid–liquid phase separation, yielding membraneless organelles, allows for the sequestration and functional insulation of cellular proteins. A modularly built, synthetic membraneless organelle platform enables efficient control over endogenous cellular activities by knockdown of protein function or controlled protein release.