Co-occurrence of enzyme domains guides the discovery of an oxazolone synthetase

June 7th, 2021 by Tristan de Rond

Nature Chemical Biology, Published online: 07 June 2021; doi:10.1038/s41589-021-00808-4

A genome-mining approach targeted to enzyme domains that co-occur in a single protein (CO-ED) facilitates the discovery and characterization of an oxazolone synthetase involved in the biosynthesis of a series of oxazolone-containing natural products.
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