Iron-sulfur proteins hiding in plain sight
June 17th, 2015 by Tracey A Rouault
Nature Chemical Biology 11, 442 (2015). doi:10.1038/nchembio.1843
Author: Tracey A Rouault
Recent studies suggest that iron-sulfur (Fe-S) proteins may be unexpectedly abundant and functionally diverse in mammalian cells, but their identification still remains difficult. The use of informatics along with traditional spectroscopic analyses could be key to discovering new Fe-S proteins and validating their functional roles.