Dynamics of transcription–translation coordination tune bacterial indole signaling
December 23rd, 2019 by Tianmin Wang
Nature Chemical Biology, Published online: 23 December 2019; doi:10.1038/s41589-019-0430-3
The authors utilize fluorescence-activated cell sorting coupled with next-generation sequencing, as well as dynamic modeling, to study the molecular mechanism underlying indole signaling and reveal different roles of the two ends of tnaC in coordinating transcription and translation.