Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1

April 15th, 2021 by Thomas Kryza

Nature Chemical Biology, Published online: 15 April 2021; doi:10.1038/s41589-021-00783-w

A substrate-biased activity-based probe technology was developed to enable relatively facile identification of proteases responsible for specific proteolytic events in complex biological milieu, revealing that urokinase regulates CDCP1 proteolysis.
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