Accurate annotation of human protein-coding small open reading frames
December 9th, 2019 by Thomas F. Martinez
Nature Chemical Biology, Published online: 09 December 2019; doi:10.1038/s41589-019-0425-0
An improved workflow combining de novo transcriptome assembly and Ribo-seq validated by cellular antigen display is developed to maximize small peptide discovery, leading to identification of thousands of unannotated protein-coding smORFs.