Identification of a radical SAM enzyme involved in the synthesis of archaeosine
November 18th, 2019 by Takashi Yokogawa
Nature Chemical Biology, Published online: 18 November 2019; doi:10.1038/s41589-019-0390-7
Euryarchaeal ArcS alone cannot produce G+-containing tRNA but works as a lysine transferase to produce a lysine adduct intermediate, which finally forms G+-containing tRNA in the presence of a newly identified SAM enzyme, RaSEA.