Designed peptides that assemble into cross-α amyloid-like structures
July 30th, 2018 by Shao-Qing Zhang
Designed peptides that assemble into cross-α amyloid-like structures
Designed peptides that assemble into cross-α amyloid-like structures, Published online: 30 July 2018; doi:10.1038/s41589-018-0105-5
Structural analysis reveals how certain designed peptides adopt unusual spiraling cross-α amyloid-like structures and also rearrange to helical polymers upon mutation of small nonpolar residues that are critical for packing and stabilization.