A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation
December 18th, 2017 by Sarah Stöcker
A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation
A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation, Published online: 18 December 2017; doi:10.1038/nchembio.2536
Cytosolic 2-Cys peroxiredoxins can enable, rather than compete with, rapid thiol oxidation by relaying H2O2-derived oxidizing equivalents to other proteins, suggesting a broadened role for peroxiredoxins as sensors and transmitters of H2O2 signals.