Selective regulation of human TRAAK channels by biologically active phospholipids
September 28th, 2020 by Samantha Schrecke
Nature Chemical Biology, Published online: 28 September 2020; doi:10.1038/s41589-020-00659-5
Native ion mobility mass spectrometry reveals two isoforms of the two-pore domain K+ channel K2P4.1 have distinct binding preferences for lipids and show a relationship between the strength of individual lipid binding events and channel activity.