Junction resolving enzymes use multivalency to keep the Holliday junction dynamic
January 21st, 2019 by Ruobo Zhou
Junction resolving enzymes use multivalency to keep the Holliday junction dynamic
Junction resolving enzymes use multivalency to keep the Holliday junction dynamic, Published online: 21 January 2019; doi:10.1038/s41589-018-0209-y
Single-molecule analysis reveals a novel binding state of Holliday junction (HJ) resolving enzymes where the enzymes partially dissociate from the HJ and allowing nearly unencumbered HJ dynamics, suggesting coupled branch migration and HJ resolution.