Topology-dependent interference of synthetic gene circuit function by growth feedback
April 6th, 2020 by Rong Zhang
Nature Chemical Biology, Published online: 06 April 2020; doi:10.1038/s41589-020-0509-x
Synthetic circuit-host interactions affect the performance synthetic biology systems. Analysis of two bi-stable switch circuits reveals differential effects of host growth on circuit memory, which is dependent on the network topology of the circuit.