Structure and functional reselection of the Mango-III fluorogenic RNA aptamer
April 15th, 2019 by Robert J. Trachman III
Structure and functional reselection of the Mango-III fluorogenic RNA aptamer
Structure and functional reselection of the Mango-III fluorogenic RNA aptamer, Published online: 15 April 2019; doi:10.1038/s41589-019-0267-9
Structural analysis of Mango-III in complex with fluorophores reveals a globular architecture and a planar conformation of fluorophores. Structure-guided mutation and functional reselection identified two mutants with improved fluorescence intensity.