Erratum: Protein dynamics: Tuning disorder propensity in p53

January 20th, 2015 by Richard W Kriwacki

Nature Chemical Biology 11, 172 (2015). doi:10.1038/nchembio0215-172b

Author: Richard W Kriwacki

Protein dynamics: Tuning disorder propensity in p53

November 13th, 2014 by Richard W Kriwacki

Nature Chemical Biology 10, 987 (2014). doi:10.1038/nchembio.1692

Author: Richard W Kriwacki

The dynamic interplay between p53 and Mdm2 triggers cell cycle arrest after DNA damage. A new study reveals that disorder in the transactivation domain of p53 is important for tuning this negative feedback system to ensure normal cellular signaling responses.