Enzymology: A radical finding

September 14th, 2014 by Rebecca J M Goss

Nature Chemical Biology 10, 878 (2014). doi:10.1038/nchembio.1649

Authors: Rebecca J M Goss & Sabine Grüschow

A new family of radical halogenases has been discovered that regio- and stereoselectively chlorinates the unactivated carbon center of indolemonoterpenoid substrates without the prerequisite for the substrate to be bound to a protein carrier.