Establishment of the PAR-1 cortical gradient by the aPKC-PRBH circuit
September 3rd, 2018 by Ravikrishna Ramanujam
Establishment of the PAR-1 cortical gradient by the aPKC-PRBH circuit
Establishment of the PAR-1 cortical gradient by the aPKC-PRBH circuit, Published online: 03 September 2018; doi:10.1038/s41589-018-0117-1
The asymmetric cortical gradient of PAR-1 is patterned via an integration of its cortical exclusion and stabilization by a circuit consisting of aPKC and the PRBH protein PAR-2.