August 19th, 2019 by Priscille Brodin

Nature Chemical Biology, Published online: 19 August 2019; doi:10.1038/s41589-019-0347-x

An unusual terpene nucleoside, 1-TbAd, made by pathogenic mycobacteria acts as an antacid to block mycobacterial degradation in host cell vacuoles. The antacid activity acts to reduce acidity by neutralizing the pH of these degradative cell organelles.