Metabolic engineering: Biosensor keeps DOPA on track

May 18th, 2015 by Pamela Peralta-Yahya

Nature Chemical Biology 11, 450 (2015). doi:10.1038/nchembio.1830

Author: Pamela Peralta-Yahya

Biosensors are emerging as an important tool to evolutionarily engineer metabolic pathway enzymes for the microbial production of chemicals. A colorimetric biosensor used to increase dopamine levels in yeast now enables the production of benzylisoquinoline alkaloids from glucose.