Peering into the cellular cycle
May 25th, 2021 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 25 May 2021; doi:10.1038/s41589-021-00814-6
The development of chemical tools and small-molecule inhibitors enables the resolution of critical cellular processes with high spatial and temporal precision.Voices of chemical biology
December 16th, 2020 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 16 December 2020; doi:10.1038/s41589-020-00714-1
We asked a collection of chemical biologists, “What is the most exciting frontier area in chemical biology and what key technology is needed to advance knowledge and applications in this area?” and reveal some of the perspectives we received.Delimiting lipids
November 16th, 2020 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 16 November 2020; doi:10.1038/s41589-020-00701-6
This themed issue features a collection of articles that explore long-standing questions in the study of lipids and membranes.Hijacking protein degradation
October 16th, 2020 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 16 October 2020; doi:10.1038/s41589-020-00685-3
Targeted protein degradation provides a powerful complement to small-molecule inhibition in modulating protein activity and allows access to otherwise intractable drug targets.15 years of <i>Nature Chemical Biology</i>
May 22nd, 2020 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 22 May 2020; doi:10.1038/s41589-020-0560-7
Over the past decade and a half, chemical biology has crystallized as a discipline and extended its reach into new scientific areas, but the field’s greatest promise lies ahead.Greatest hits
May 22nd, 2020 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 22 May 2020; doi:10.1038/s41589-020-0546-5
We present a selection of papers published in Nature Chemical Biology over the past five years that reflect the diversity and excitement of chemical biology research.Voices of chemical biology
May 22nd, 2020 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology, Published online: 22 May 2020; doi:10.1038/s41589-020-0543-8
We asked a collection of chemical biologists, “What was the most exciting research achievement or technology innovation in chemical biology in the last five years?” and reveal some of the perspectives we received.Altering form for function
February 14th, 2018 by Nature Chemical Biology - Issue - nature.com science feeds
Altering form for function
Altering form for function, Published online: 14 February 2018; doi:10.1038/nchembio.2582
Elucidating the mechanisms by which biomolecules are chemically modified and how these alterations regulate biological pathways represents a leading frontier in chemical biology.Hints of hidden chemistry
July 18th, 2017 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology 13, 815 (2017). doi:10.1038/nchembio.2449
Biosynthetic pathways harbor diverse enzyme functions, and identifying those that catalyze unusual or synthetically challenging transformations offers new routes for biocatalytic development.
Shaping embryonic development
May 17th, 2017 by Nature Chemical Biology - Issue - nature.com science feeds
Nature Chemical Biology 13, 559 (2017). doi:10.1038/nchembio.2403
The growing intersection between chemical tools and principles and developmental biology is providing new insights into the molecular-level details of developmental processes.