A stress-free stress response

July 23rd, 2020 by Nadia Cummins

Nature Chemical Biology, Published online: 23 July 2020; doi:10.1038/s41589-020-0616-8

A new molecule that specifically activates a key protein homeostasis pathway has been identified. The ability to initiate the IRE1–XBP1s branch of the unfolded protein response opens up new avenues for basic research and treatment of disease.