DNA Damage: Walking the edge

March 18th, 2014 by Melissa N Locke

Nature Chemical Biology 10, 243 (2014). doi:10.1038/nchembio.1483

Authors: Melissa N Locke & Michael Rape

An inhibitor of the deubiquitinase complex USP1-UAF1 highlights the requirement for reversible ubiquitination in DNA repair pathways that are critical for human development and disease.