A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

March 9th, 2020 by Maulik S. Jani

Nature Chemical Biology, Published online: 09 March 2020; doi:10.1038/s41589-020-0491-3

A pair of fluorescent DNA-based probes for nitric oxide reveals that nitric oxide synthase 3 activity in the trans-Golgi network is essential for Golgi structural integrity, despite being tenfold less active there than at the plasma membrane.
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