Immunology: Glyco-engineering ‘super-self’

December 17th, 2013 by Matthew S Macauley

Nature Chemical Biology 10, 7 (2014). doi:10.1038/nchembio.1415

Authors: Matthew S Macauley & James C Paulson

Altered glycosylation of cancer cells confers phenotypic changes that promote spread and evasion of immune responses. A new method for engineering cell surface glycans is providing insights into these mechanisms.