Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy

March 4th, 2021 by Liguo Wang

Nature Chemical Biology, Published online: 04 March 2021; doi:10.1038/s41589-021-00742-5

A selective and potent CDK2 degrader was developed that induced differentiation of acute myeloid leukemia cell lines and primary patient cells.
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