Antimicrobial mechanisms: A sponge against fungal infections

April 20th, 2014 by Karl Lohner

Nature Chemical Biology 10, 411 (2014). doi:10.1038/nchembio.1518

Author: Karl Lohner

The finding that the antifungal activity of amphotericin B is primarily due to its ability to extract ergosterol from fungal membranes suggests a new rationale for drug design, which should lead to advanced treatments, particularly for invasive fungal infections.