Fighting PRC1 via the RING

June 21st, 2021 by Joshua P. Plotnik

Nature Chemical Biology, Published online: 21 June 2021; doi:10.1038/s41589-021-00819-1

Over the past two decades, inhibitors of the polycomb repressor complex (PRC) have been driven from bench to bedside. New chemical compounds targeting the RING1B in polycomb repressor complex 1 (PRC1) add important tools to regulate polycomb functions.