Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase
June 25th, 2018 by Jiasong Li
Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase
Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase, Published online: 25 June 2018; doi:10.1038/s41589-018-0085-5
Engineered variants of cysteine dioxygenase containing a halogen-substituted tyrosine analog provide insights into the process of Cys–Tyr cross-link formation and indicate that the enzyme can catalyze oxidative cleavage of a carbon–fluorine bond.