Engineering synergy in biotechnology

April 17th, 2014 by Jens Nielsen

Nature Chemical Biology 10, 319 (2014). doi:10.1038/nchembio.1519

Authors: Jens Nielsen, Martin Fussenegger, Jay Keasling, Sang Yup Lee, James C Liao, Kristala Prather & Bernhard Palsson

Biotechnology is a central focus in efforts to provide sustainable solutions for the provision of fuels, chemicals and materials. On the basis of a recent open discussion, we summarize the development of this field, highlighting the distinct but complementary approaches provided by metabolic engineering and synthetic biology for the creation of efficient cell factories to convert biomass and other feedstocks to desired chemicals.