Genetic engineering: Chemical control for CRISPR editing

November 7th, 2016 by Isaac B Hilton

Nature Chemical Biology 13, 2 (2017). doi:10.1038/nchembio.2243

Authors: Isaac B Hilton & Charles A Gersbach

New approaches allow tight control over Cas9 activity using chemical induction. These studies expand the ability to rapidly induce and suppress Cas9-mediated nuclease activity and conditionally modulate the multiplex regulation of endogenous gene expression.