A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing
December 9th, 2019 by Hai T. Dao
Nature Chemical Biology, Published online: 09 December 2019; doi:10.1038/s41589-019-0413-4
A photocrosslinking-based nucleosome profiling approach is used to identify a conserved basic motif in the ISWI remodeler SNF2h that anchors it to the acidic patch of nucleosome and enables nucleosome sliding activity.