Enzymatic C–H activation of aromatic compounds through CO<sub>2</sub> fixation
July 27th, 2020 by Godwin A. Aleku
Nature Chemical Biology, Published online: 27 July 2020; doi:10.1038/s41589-020-0603-0
Biocatalytic cascade reactions using engineered variants of ferulic acid decarboxylase coupled to carboxylic acid reductase utilize carbon dioxide fixation to enable the carboxylation and functionalization of styrene and other aromatic compounds.