Author Correction: Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme
June 12th, 2020 by Gloria Yang
Nature Chemical Biology, Published online: 12 June 2020; doi:10.1038/s41589-020-0588-8
Author Correction: Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzymeHigher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme
October 21st, 2019 by Gloria Yang
Nature Chemical Biology, Published online: 21 October 2019; doi:10.1038/s41589-019-0386-3
Ancestral protein reconstruction followed by biochemical and structural analyses characterizes the evolutionary trajectory of methyl-parathion hydrolase from an ancestral dihydrocoumarin hydrolase through the accumulation of five key mutations.