Proteostasis: Chaperoning for hearing loss

May 18th, 2016 by Gergely L Lukacs

Nature Chemical Biology 12, 388 (2016). doi:10.1038/nchembio.2091

Author: Gergely L Lukacs

A small molecule has been identified that can mitigate the progression of an inherited form of deafness in transgenic mice by stabilizing mutant clarin-1, an essential component of a multimolecular complex of the mechanotransduction apparatus of hair cells in the inner ear.