Stress response: PARP1 911

February 17th, 2015 by Florian J Bock

Nature Chemical Biology 11, 179 (2015). doi:10.1038/nchembio.1756

Authors: Florian J Bock & Paul Chang

Although resveratrol is thought to provide many beneficial health effects, its cellular targets and mechanism of function are still under investigation. A new study found that resveratrol binds to tyrosyl transfer-RNA synthetase, resulting in the activation of the stress response effector PARP1.