A genetics-free method for high-throughput discovery of cryptic microbial metabolites
January 7th, 2019 by Fei Xu
A genetics-free method for high-throughput discovery of cryptic microbial metabolites
A genetics-free method for high-throughput discovery of cryptic microbial metabolites, Published online: 07 January 2019; doi:10.1038/s41589-018-0193-2
A combination of elicitor screening to induce expression of silent biosynthetic gene clusters with imaging mass spectrometry to visualize the resulting metabolome enables the discovery of nine cryptic natural products.