A widespread role for SLC transmembrane transporters in resistance to cytotoxic drugs
March 9th, 2020 by Enrico Girardi
Nature Chemical Biology, Published online: 09 March 2020; doi:10.1038/s41589-020-0483-3
A set of CRISPR–Cas9-based genetic screens in a haploid human cell line identifies more than 200 gene–drug associations involving solute carriers (SLCs), transporters important for the uptake and activity of cytotoxic drugs.