Unfolding of a ClC chloride transporter retains memory of its evolutionary history
March 26th, 2018 by Duyoung Min
Unfolding of a ClC chloride transporter retains memory of its evolutionary history
Unfolding of a ClC chloride transporter retains memory of its evolutionary history, Published online: 26 March 2018; doi:10.1038/s41589-018-0025-4
A single-molecule forced unfolding of E. coli chloride transporter ClC-ec1 shows that the N- and C-terminal halves of the protein unfold independently, with exposed polar surfaces stabilized by membrane lipid head groups and water.Mapping the energy landscape for second-stage folding of a single membrane protein
October 19th, 2015 by Duyoung Min
Nature Chemical Biology 11, 981 (2015). doi:10.1038/nchembio.1939
Authors: Duyoung Min, Robert E Jefferson, James U Bowie & Tae-Young Yoon