Mechanism of regulation and neutralization of the AtaR–AtaT toxin–antitoxin system
February 4th, 2019 by Dukas Jurėnas
Mechanism of regulation and neutralization of the AtaR–AtaT toxin–antitoxin system
Mechanism of regulation and neutralization of the AtaR–AtaT toxin–antitoxin system, Published online: 04 February 2019; doi:10.1038/s41589-018-0216-z
Structural and biochemical analysis of the AtaR–AtaT toxin–antioxin system reveals that AtaR traps AtaT in a precatalytic monomeric state and forms a heterohexameric complex to neutralize AtaT and repress transcription of the operon.AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet
April 3rd, 2017 by Dukas Jurėnas
Nature Chemical Biology 13, 640 (2017). doi:10.1038/nchembio.2346
Authors: Dukas Jurėnas, Sneha Chatterjee, Albert Konijnenberg, Frank Sobott, Louis Droogmans, Abel Garcia-Pino & Laurence Van Melderen