Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease
January 11th, 2021 by Dan Li
Nature Chemical Biology, Published online: 11 January 2021; doi:10.1038/s41589-020-00708-z
This Perspective summarizes the recent advances in the structural diversity of amyloid fibrils and discusses the roles of post-translational modifications and chemical cofactors in the conformational determination of fibril polymorphs.