Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase

October 23rd, 2017 by Chia-Wei Hu

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase, Published online: 23 October 2017; doi:10.1038/nchembio.2494

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N-Acetylglucosamine derivatives equipped with electrophilic groups and handles for subsequent chemical tagging are useful probes of substrate recognition by O-GlcNAc transferases and enable the capture of transient protein substrates of these enzymes.

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