Toward an orthogonal central dogma
January 16th, 2018 by Chang C Liu
Toward an orthogonal central dogma
Toward an orthogonal central dogma, Published online: 16 January 2018; doi:10.1038/nchembio.2554
The central dogma processes of DNA replication, transcription, and translation are responsible for the maintenance and expression of every gene in an organism. An orthogonal central dogma may insulate genetic programs from host regulation and allow expansion of the roles of these processes within the cell.