A gene signal amplifier platform for monitoring the unfolded protein response
March 9th, 2020 by Carlos A. Origel Marmolejo
Nature Chemical Biology, Published online: 09 March 2020; doi:10.1038/s41589-020-0497-x
Engineering of a synthetic circuit that couples transcriptional and protein turnover regulation to a fluorescent protein readout enables sensitive monitoring and amplification of gene expression signals from the unfolded protein response pathway.