mRNA regulation: A patch for a splice
June 17th, 2015 by Benjamin L Miller
Nature Chemical Biology 11, 454 (2015). doi:10.1038/nchembio.1839
Author: Benjamin L Miller
The spliceosome is an immensely complex molecular machine tasked with stitching together coding regions of genes. New work reveals how a small molecule can affect this machinery in a model of spinal muscular atrophy, a disease linked to aberrant splicing.