mRNA regulation: A patch for a splice

June 17th, 2015 by Benjamin L Miller

Nature Chemical Biology 11, 454 (2015). doi:10.1038/nchembio.1839

Author: Benjamin L Miller

The spliceosome is an immensely complex molecular machine tasked with stitching together coding regions of genes. New work reveals how a small molecule can affect this machinery in a model of spinal muscular atrophy, a disease linked to aberrant splicing.